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sweD [2019-08-23 09:22:18]
cofactor of the [protein|8BF7EB539B53D75BD30BD30ABF27106D6A0B030B|FtsE]-[protein|E22D0F0AC56DC95AFC02E7F55FCD5FAA44B6B490|FtsX] complex
function
control of [protein|4F9D70C4BB4FCA809BEAC341C3F8122FB7FD8872|CwlO] activity in peptidoglycan elongation
product
cofactor of the [protein|8BF7EB539B53D75BD30BD30ABF27106D6A0B030B|FtsE]-[protein|E22D0F0AC56DC95AFC02E7F55FCD5FAA44B6B490|FtsX] complex
Genomic Context
categories
[category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
2,576,367 2,576,720
The protein
[SW|Localization]
cell membrane (according to UniProt)Expression and Regulation
Operons
genes
[gene|5F184E491602D548AAE8E6D598BB742513770F73|sweD]-[gene|0BC657B63EE124B17FDA7914262E706B2CC9ABC1|sweC]
description
[Pubmed|22383849]
regulatory mechanism
[protein|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A]: repression, [Pubmed|14651647], in [regulon|2C54FE2ADC82FF414D732018C90649D477A925AD|Spo0A regulon]regulation
repressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|14651647]view in new tabadditional information
the mRNA is cleaved by [protein|BAB297D18F94FFA67B8D12A684AB4D1BCDFB4981|RNase III] [PubMed|26883633]Biological materials
Mutant
MGNA-C483 (yqzD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2481 NBRP B. subtilis, Japan]BKE24930 ([gene|5F184E491602D548AAE8E6D598BB742513770F73|sweD]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE24930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTTTCATCACCTTCTAT, downstream forward: _UP4_AAAGATAATGAGAAGGTGCTBKK24930 ([gene|5F184E491602D548AAE8E6D598BB742513770F73|sweD]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK24930 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACGTTTCATCACCTTCTAT, downstream forward: _UP4_AAAGATAATGAGAAGGTGCTReferences
14651647,26883633,31437162